I've been using firefox 3.0 release candidate 1 for the last few days and it is fantastic. Unlike firefox 2.0 this beasty hasn't crashed once. It seems to use less memory too.
The best thing: GMail and GReader are so, so, so much faster to open and use. Considering they're the main applications I use these days ... that's good. I held off upgrading until now - despite my friend Graeme advising me to switch for months - because the Better Gmail 2 extension wasn't compatable. It is now.
I've also just added Better GReader and the preview option is really rather handy for all those blogs which only show a snippet of the full post. It's a very elegant implementation.